Deciphering the signals specifying the proepicardium.
نویسنده
چکیده
CIRCULATION RESEARCH (ISSN 0009-7330) is published semimonthly except one issue per month in January and December and three issues per month in April and September by Lippincott Williams & Wilkins, at 12107 Insurance Way, Hagerstown, MD 21740. Business offices are located at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103. Production offices are located at 351 West Camden Street, Baltimore, MD 21201-2436. Individuals may subscribe for their personal use at the following annual rates: Domestic: $240 for members and $520 for nonmembers. International: $297 for members of an American Heart Association scientific council and $650 for nonmembers. Contact Lippincott Williams & Wilkins for single copy rates and subscription rates for medical professionals in training and for libraries, reading rooms, and other multiple-use institutions. Periodicals postage paid at Hagerstown, MD, and additional mailing offices. POSTMASTER: Send address changes to CIRCULATION RESEARCH, American Heart Association, Lippincott Williams & Wilkins, 12107 Insurance Way, Hagerstown, MD 21740. Featured Article Online supplementary information Online movie files Available at http://circres.ahajournals.org
منابع مشابه
Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.
RATIONALE The proepicardium is a transient structure comprising epicardial progenitor cells located at the posterior limit of the embryonic cardiac inflow. A network of signals regulates proepicardial cell fate and defines myocardial and nonmyocardial domains at the venous pole of the heart. During cardiac development, epicardial-derived cells also contribute to coronary vessel morphogenesis. ...
متن کاملEvolutionary Origin of the Proepicardium
The embryonic epicardium and the cardiac mesenchyme derived from it are critical to heart development. The embryonic epicardium arises from an extracardiac progenitor tissue called the proepicardium, a proliferation of coelomic cells located at the limit between the liver and the sinus venosus. A proepicardium has not been described in invertebrates, and the evolutionary origin of this structur...
متن کاملInduction of the Proepicardium.
The proepicardium is a transient extracardiac embryonic tissue that gives rise to the epicardium and a number of coronary vascular cell lineages. This important extracardiac tissue develops through multiple steps of inductive events, from specification of multiple cell lineages to morphogenesis. This article will review our current understanding of inductive events involved in patterning of the...
متن کاملSignaling during epicardium and coronary vessel development.
The epicardium, the tissue layer covering the cardiac muscle (myocardium), develops from the proepicardium, a mass of coelomic progenitors located at the venous pole of the embryonic heart. Proepicardium cells attach to and spread over the myocardium to form the primitive epicardial epithelium. The epicardium subsequently undergoes an epithelial-to-mesenchymal transition to give rise to a popul...
متن کاملLeft-Right Asymmetrical Development of the Proepicardium
The proepicardium (PE) is a cluster of cells that forms on the cardiac inflow tract and gives rise to the epicardium and connective tissue and largely contributes to the coronary vasculature. In many vertebrates, the PE undergoes left-right asymmetrical development. While PE cells and marker genes can be initially found on both sides, only the right-sided PE will fully develop and ultimately de...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Circulation research
دوره 106 12 شماره
صفحات -
تاریخ انتشار 2010